VERY simply stated, methylation is a process that happens in all cells of the body so that you’re able to make the chemicals you need to function. It is tightly linked to folate metabolism and requires vitamin B12.

What exactly needs methylation reactions? The short list would include cellular repair, detoxification, neurotransmitter production, proper immune system function, and specifically important in my case, inactivating histamine. Those are some important functions, indeed.

MTHFR stands for methyl-tetrahydrofolate reductase which is the enzyme which is responsible for methylation; there are several genetic variants which result in suboptimal methylation. I have one copy of C677T gene for MTHFR. read more